Nowadays, excess weight is a widespread problem which is growing due to the quality of food and contemporary tendency in nutrition characterized by irregular and improper meals. A lot of medicines supporting weight loss achieved by physical exercises and diets have been created to solve the problem more efficiently. Their main aim is to improve and keep the result, but still there are some differences. Here we are going to consider Phentermine and Sibutramine - two weight loss drugs, which are rather popular and often prescribed by dietitians.
Phentermine and Sibutramine are medications that are effective for treatment of obese people. These medications were designed for people with BMI over 30 or people with BMI over 27 but with high amount of fat in the blood, type 2 diabetes and hypertension.
Although Phentermine and Sibutramine are alike in their effect, the principles they work on are different. Sibutramine reduces the appetite by intensifying neuromediators’ influence on the satiety centre of ventromedial area of hypothalamus, increasing the metabolic rate and thermogenesis which hastens weight loss. Sibutramine reduces the secondary usage of serotonin, dopamine and norepinaphrine. On the contrary, Phentermine stimulates the release of norepinaphrine and dopamine in nerve-endings, thus, decreasing the food intake and increasing resting energy expenditure.
- Reductil pills are prescribed as a long-term therapy of obesity. The maximum recommended duration of using Reductil pills is 2 years.
- Phentermine pills are prescribed as a short-term therapy of obesity. The maximum recommended duration of using Phentermine pills is 3 months.
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