Obesity is a worldwide problem. As we gain weight as a population, our health declines. Drug manufacturers are scrambling to develop treatments for obesity. Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug Orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
In human trials, Cetilistat was shown to produce similar weight loss to Orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, and flatulence. It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.
Cetilistat is generally taken with food, or even up to 1 hour after having food. If you skip a meal or if your food does not contain any fat, you can skip taking Cetilistat for that meal. The exact dosage and period of treatment will depend on your specific diagnosis and overall health and will be prescribed by your doctor.
Cetislim is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.
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